HCA Data Portal

Tier 1 Metadata

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Dataset

FieldDescription
Study PI
Required

string (multivalued)

Description
Example
Sarah,A,Teichmann
Source
HCA
BioNetworks
AnnData Location
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Batch Condition
Recommended

string (multivalued)

Description
Allowed Values
Example
["patient", "seqBatch"]
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more
Default Embedding
Recommended

string

Description
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more
Sequencing Platform
Recommended

string

Description
Allowed Values
Example
EFO:0008563
Rationale
Source
HCA
BioNetworks
AnnData Location
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Assay Ontology Term ID
Required

string

Description
Allowed Values
Example
EFO:0009922
Rationale
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more
Reference Genome
Required

string

Description
Allowed Values
Example
GRCh38
GRCh37
Rationale
Source
HCA
BioNetworks
AnnData Location
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Alignment Software
Required

string

Description
Example
cell ranger 3.0.1
kallisto bustools
GSNAP
Rationale
Source
HCA
BioNetworks
AnnData Location
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Intron Inclusion
Recommended

string

Description
Allowed Values
Example
yes
no
Rationale
Source
HCA
BioNetworks
AnnData Location
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Sequenced Fragment
Required

string

Description
Allowed Values
Example
3 prime tag
full length
Rationale
Source
HCA
BioNetworks
AnnData Location
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Gene Annotation Version
Required

string

Description
Allowed Values
Example
v110
GCF_000001405.40
Rationale
Source
HCA
BioNetworks
AnnData Location
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Comments
Recommended

string

Description
Source
HCA
BioNetworks
AnnData Location
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Protocol URL
Recommended

string

Description
Example
https://www.biorxiv.org/conte nt/early/2017/09/24/193219
Rationale
Source
HCA
BioNetworks
AnnData Location
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Title
Required

string

Description
Example
Cells of the adult human heart collection is "All — Cells of the adult human heart"
Rationale
Source
CELLxGENE Schema
BioNetworks
AnnData Location
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Ambient Count Correction
Required

string

Description
Example
none
soupx
cellbender
Source
HCA
BioNetworks
AnnData Location
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Doublet Detection
Required

string

Description
Example
none
doublet_finder
manual
Source
HCA
BioNetworks
AnnData Location
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Embedding
Required

numpy.ndarray

Description
Allowed Values
Example
X_tSNE
X_UMAP
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more

Donor

FieldDescription
Donor ID
Required

string

Description
Allowed Values
Example
CR_donor_1
MM_donor_1
LR_donor_2
Rationale
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more
Organism Ontology Term ID
Required

string

Description
Allowed Values
Example
NCBITaxon:9606
NCBITaxon:10090
Rationale
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more
Manner of Death
Required

string

Description
Allowed Values
Example
1
2
3
4
0
unknown
not applicable
Rationale
Source
HCA
BioNetworks
AnnData Location
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Sex Ontology Term ID
Required

string

Description
Allowed Values
Example
PATO:0000383 for female, PATO:0000384 for male
Rationale
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more

Sample

FieldDescription
Sample ID
Required

string

Description
Example
SC24
SC25
SC28
Rationale
Source
HCA
BioNetworks
AnnData Location
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Tissue Ontology Term ID
Required

string

Description
Allowed Values
Example
UBERON:0001828
UBERON:0000966
Rationale
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more
Tissue Free Text
Recommended

string

Description
Example
terminal ileum
Rationale
Source
HCA
BioNetworks
AnnData Location
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Sample Source
Required

string

Description
Allowed Values
Example
surgical donor
postmortem donor
Rationale
Source
HCA
BioNetworks
AnnData Location
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Sample Collection Method
Required

string

Description
Allowed Values
Example
biopsy
brush
surgical resection
Rationale
Source
HCA
BioNetworks
AnnData Location
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Tissue Type
Required

string

Description
Allowed Values
Example
tissue
organoid
cell culture
Rationale
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more
Sampled Site Condition
Required

string

Description
Allowed Values
Example
healthy
diseased
adjacent
Rationale
Source
HCA
BioNetworks
AnnData Location
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Disease Ontology Term ID
Required

string

Description
Allowed Values
Example
MONDO:0005385
PATO:0000461
Rationale
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more
Sample Preservation Method
Required

string

Description
Allowed Values
Example
fresh
frozen at -70C
Rationale
Source
HCA
BioNetworks
AnnData Location
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Suspension Type
Required

string

Description
Allowed Values
Example
cell
nucleus
na
Rationale
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more
Is Primary Data
Required

string

Description
Allowed Values
Example
true
false
Rationale
Source
HCA
BioNetworks
AnnData Location
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Development Stage Ontology Term ID
Required

string

Description
Allowed Values
Example
HsapDv:0000237
unknown
Rationale
Source
HCA
BioNetworks
AnnData Location
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Radial Tissue Term
Required

string

Description
Allowed Values
Example
EPI
LP
MUSC
SUB
MLN
PP
Source
HCA
BioNetworks
AnnData Location
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Cell Enrichment
Required

string

Description
Allowed Values
Example
CL:0000057+
na
Rationale
Source
HCA
BioNetworks
AnnData Location
Show more
Sample Collection Year
Recommended

string

Description
Example
2018
Rationale
Source
HCA
BioNetworks
AnnData Location
Show more
Sample Collection Site
Recommended

string

Description
Allowed Values
Example
AIDA_site_1
AIDA_site_2
Rationale
Source
HCA
BioNetworks
AnnData Location
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Sample Collection Relative Time Point
Recommended

string

Description
Example
sampleX_day1
Rationale
Source
HCA
BioNetworks
AnnData Location
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Cell Number Loaded
Recommended

integer

Description
Example
5000
4000
Rationale
Source
HCA
BioNetworks
AnnData Location
Show more
Cell Viability Percentage
Recommended

decimal

Description
Example
88
95
93.5
Rationale
Source
HCA
BioNetworks
AnnData Location
Show more
Institute
Required

string

Description
Example
EMBL-EBI
Genome Institute of Singapore
Rationale
Source
HCA
BioNetworks
AnnData Location
Show more
Author Batch Notes
Recommended

string

Description
Example
Batch run by different personnel on different days
Rationale
Source
HCA
BioNetworks
AnnData Location
Show more

Library

FieldDescription
Library ID
Required

string

Description
Example
A24
NK_healthy_001
Rationale
Source
HCA
BioNetworks
AnnData Location
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Library ID Repository
Recommended

string

Description
Example
GSM1684095
Rationale
Source
HCA
BioNetworks
AnnData Location
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Library Preparation Batch
Strongly Recommended

string

Description
Example
batch01
batch02
Rationale
Source
HCA
BioNetworks
AnnData Location
Show more
Library Sequencing Run
Strongly Recommended

string

Description
Example
run1
NV0087
Rationale
Source
HCA
BioNetworks
AnnData Location
Show more

Cell

FieldDescription
Author Cell Type
Recommended

string

Description
Example
Goblet cell
microglia
Rationale
Source
HCA
BioNetworks
AnnData Location
Show more
Cell Type Ontology Term ID
Recommended

string

Description
Allowed Values
Example
CL:0001204
Rationale
Source
HCA
BioNetworks
AnnData Location
Show more

Feature

FieldDescription
Feature ID
Required

string

Description
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more
Feature is Filtered
Required

boolean

Description
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more

Matrix Layers

FieldDescription
Matrix Layer
Required

oneOf(numpy.ndarray, scipy.sparse.csr_matrix)

Description
Allowed Values
Source
CELLxGENE Schema
BioNetworks
AnnData Location
Show more
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v2.14.1-5a04119-dcp60