Nervous System Network

Kimberly Siletti, Rebecca Hodge, Alejandro Mossi Albiach, Ka Wai Lee, Song-Lin Ding, Lijuan Hu, Peter Lönnerberg, Trygve Bakken, Tamara Casper, Michael Clark, Nick Dee, Jessica Gloe, Daniel Hirschstein, Nadiya V. Shapovalova, C. Dirk Keene, Julie Nyhus, Herman Tung, Anna Marie Yanny, Ernest Arenas, Ed S. Lein, Sten Linnarsson. (2023). Transcriptomic diversity of cell types across the adult human brain. Science. DOI: 10.1126/science.add7046

Yang Eric Li, Sebastian Preissl, Michael Miller, Nicholas D. Johnson, Zihan Wang, Henry Jiao, Chenxu Zhu, Zhaoning Wang, Yang Xie, Olivier Poirion, Colin Kern, Antonio Pinto-Duarte, Wei Tian, Kimberly Siletti, Nora Emerson, Julia Osteen, Jacinta Lucero, Lin Lin, Qian Yang, Quan Zhu, Nathan Zemke, Sarah Espinoza, Anna Marie Yanny, Julie Nyhus, Nick Dee, Tamara Casper, Nadiya Shapovalova, Daniel Hirschstein, Rebecca D. Hodge, Sten Linnarsson, Trygve Bakken, Boaz Levi, C. Dirk Keene, Jingbo Shang, Ed Lein, Allen Wang, M. Margarita Behrens, Joseph R. Ecker, Bing Ren. (2023). A comparative atlas of single-cell chromatin accessibility in the human brain. Science. DOI: 10.1126/science.adf7044

Wei Tian, Jingtian Zhou, Anna Bartlett, Qiurui Zeng, Hanqing Liu, Rosa G. Castanon, Mia Kenworthy, Jordan Altshul, Cynthia Valadon, Andrew Aldridge, Joseph R. Nery, Huaming Chen, Jiaying Xu, Nicholas D. Johnson, Jacinta Lucero, Julia K. Osteen, Nora Emerson, Jon Rink, Jasper Lee, Yang E. Li, Kimberly Siletti, Michelle Liem, Naomi Claffey, Carolyn O’Connor, Anna Marie Yanny, Julie Nyhus, Nick Dee, Tamara Casper, Nadiya Shapovalova, Daniel Hirschstein, Song-Lin Ding, Rebecca Hodge, Boaz P. Levi, C. Dirk Keene, Sten Linnarsson, Ed Lein, Bing Ren, M. Margarita Behrens, Joseph R. Ecker. (2023). Single-cell DNA methylation and 3D genome architecture in the human brain. Science. DOI: 10.1126/science.adf5357

Nikolas L. Jorstad, Jennie Close, Nelson Johansen, Anna Marie Yanny, Eliza R. Barkan, Kyle J. Travaglini, Darren Bertagnolli, Jazmin Campos, Tamara Casper, Kirsten Crichton, Nick Dee, Song-Lin Ding, Emily Gelfand, Jeff Goldy, Daniel Hirschstein, Katelyn Kiick, Matthew Kroll, Michael Kunst, Kanan Lathia, Brian Long, Naomi Martin, Delissa McMillen, Trangthanh Pham, Christine Rimorin, Augustin Ruiz, Nadiya Shapovalova, Soraya Shehata, Kimberly Siletti, Saroja Somasundaram, Josef Sulc, Michael Tieu, Amy Torkelson, Herman Tung, Edward M. Callaway, Patrick R. Hof, C. Dirk Keene, Boaz P. Levi, Sten Linnarsson, Partha P. Mitra, Kimberly Smith, Rebecca D. Hodge, Trygve E. Bakken, Ed S Lein. (2023). Transcriptomic cytoarchitecture reveals principles of human neocortex organization. Science. DOI: 10.1126/science.adf6812

Nelson Johansen, Saroja Somasundaram, Kyle J. Travaglini, Anna Marie Yanny, Maya Shumyatcher, Tamara Casper, Charles Cobbs, Nick Dee, Richard Ellenbogen, Manuel Ferreira, Jeff Goldy, Junitta Guzman, Ryder Gwinn, Daniel Hirschstein, Nikolas L. Jorstad, C. Dirk Keene, Andrew Ko, Boaz P. Levi, Jeffrey G. Ojemann, Thanh Pham, Nadiya Shapovalova, Daniel Silbergeld, Josef Sulc, Amy Torkelson, Herman Tung, Kimberly Smith, Ed S. Lein, Trygve E. Bakken, Rebecca D. Hodge, Jeremy A. Miller. (2023). Interindividual variation in human cortical cell type abundance and expression. Science. DOI: 10.1126/science.adf2359

Irene Costantini, Leah Morgan, Jiarui Yang, Yael Balbastre, Divya Varadarajan, Luca Pesce, Marina Scardigli, Giacomo Mazzamuto, Vladislav Gavryusev, Filippo Maria Castelli, Matteo Roffilli, Ludovico Silvestri, Jessie Laffey, Sophia Raia, Merina Varghese, Bridget Wicinski, Shuaibin Chang, Ichun Anderson Chen, Hui Wang, Devani Cordero, Matthew Vera, Jackson Nolan, Kimberly Nestor, Jocelyn Mora, Juan Eugenio Iglesias, Erendira Garcia Pallares, Kathryn Evancic, Jean C. Augustinack, Morgan Fogarty, Adrian V. Dalca, Matthew P. Frosch, Caroline Magnain, Robert Frost, Andre van der Kouwe, Shih-Chi Chen, David A. Boas, Francesco Saverio Pavone, Bruce Fischl, Patrick R. Hof. (2023). A cellular resolution atlas of Broca’s area. Science Advances. DOI: 10.1126/sciadv.adg3844

Fenna M. Krienen, Kirsten M. Levandowski, Heather Zaniewski, Ricardo C.H. del Rosario, Margaret E. Schroeder, Melissa Goldman, Martin Wienisch, Alyssa Lutservitz, Victoria F. Beja-Glasser, Cindy Chen, Qiangge Zhang, Ken Y. Chan, Katelyn X. Li, Jitendra Sharma, Dana McCormack, Tay Won Shin, Andrew Harrahill, Eric Nyase, Gagandeep Mudhar, Abigail Mauermann, Alec Wysoker, James Nemesh, Seva Kashin, Josselyn Vergara, Gabriele Chelini, Jordane Dimidschstein, Sabina Berretta, Benjamin E. Deverman, Ed Boyden, Steven A. McCarroll, Guoping Feng. (2023). A marmoset brain cell census reveals regional specialization of cellular identities. Science Advances. DOI: 10.1126/sciadv.adk3986

Kenneth L. Chiou, Xingfan Huang, Martin O. Bohlen, Sébastien Tremblay, Alex R. DeCasien, Diana R. O’Day, Cailyn H. Spurrell, Aishwarya A. Gogate, Trisha M. Zintel, Madeline G. Andrews, Melween I. Martínez, Lea M. Starita, Michael J. Montague, Michael L. Platt, Jay Shendure, Noah Snyder-Mackler, Cayo Biobank Research Unit. (2023). A single-cell multi-omic atlas spanning the adult rhesus macaque brain. Science Advances. DOI: 10.1126/sciadv.adh1914

Nikolas L. Jorstad, Janet H. T. Song, David Exposito-Alonso, Hamsini Suresh, Nathan Castro-Pacheco, Fenna M. Krienen, Anna Marie Yanny, Jennie Close, Emily Gelfand, Brian Long, Stephanie C. Seeman, Kyle J. Travaglini, Soumyadeep Basu, Marc Beaudin, Darren Bertagnolli, Megan Crow, Song-Lin Ding, Jeroen Eggermont, Alexandra Glandon, Jeff Goldy, Katelyn Kiick, Thomas Kroes, Delissa McMillen, Trangthanh Pham, Christine Rimorin, Kimberly Siletti, Saroja Somasundaram, Michael Tieu, Amy Torkelson, Guoping Feng, William D. Hopkins, Thomas Höllt, C. Dirk Keene, Sten Linnarsson, Steven A. McCarroll, Boudewijn P. Lelieveldt, Chet C. Sherwood, Kimberly Smith, Christopher A. Walsh, Alexander Dobin, Jesse Gillis, Ed S. Lein, Rebecca D. Hodge, Trygve E. Bakken. (2023). Comparative transcriptomics reveals human-specific cortical features. Science. DOI: 10.1126/science.ade9516

Kaiyi Zhu, Jaroslav Bendl, Samir Rahman, James M. Vicari, Claire Coleman, Tereza Clarence, Ovaun Latouche, Nadejda M. Tsankova, Aiqun Li, Kristen J. Brennand, Donghoon Lee, Guo-Cheng Yuan, John F. Fullard, Panos Roussos. (2023). Multi-omic profiling of the developing human cerebral cortex at the single-cell level. Science Advances. DOI: 10.1126/sciadv.adg3754

Seth A. Ament, Marcia Cortes-Gutierrez, Brian R. Herb, Evelina Mocci, Carlo Colantuoni, Margaret M. McCarthy. (2023). A single-cell genomic atlas for maturation of the human cerebellum during early childhood. Science Translational Medicine. DOI: 10.1126/scitranslmed.ade1283

Emelie Braun, Miri Danan-Gotthold, Lars E. Borm, Ka Wai Lee, Elin Vinsland, Peter Lönnerberg, Lijuan Hu, Xiaofei Li, Xiaoling He, Žaneta Andrusivová, Joakim Lundeberg, Roger A. Barker, Ernest Arenas, Erik Sundström, Sten Linnarsson. (2023). Comprehensive cell atlas of the first-trimester developing human brain. Science. DOI: 10.1126/science.adf1226

Chang N. Kim, David Shin, Albert Wang, Tomasz J. Nowakowski. (2023). Spatiotemporal molecular dynamics of the developing human thalamus. Science. DOI: 10.1126/science.adf9941

Brian R. Herb, Hannah J. Glover, Aparna Bhaduri, Carlo Colantuoni, Tracy L. Bale, Kimberly Siletti, Sten Linnarsson, Rebecca Hodge, Ed Lein, Arnold R. Kriegstein, Claudia A. Doege, Seth A. Ament. (2021). Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus. bioRxiv. DOI: 10.1101/2021.07.20.453090

Dmitry Velmeshev, Yonatan Perez, Zihan Yan, Jonathan E. Valencia, David R. Castaneda-Castellanos, Li Wang, Lucas Schirmer, Simone Mayer, Brittney Wick, Shaohui Wang, Tomasz Jan Nowakowski, Mercedes Paredes, Eric J. Huang, Arnold R. Kriegstein. (2023). Single-cell analysis of prenatal and postnatal human cortical development. Science. DOI: 10.1126/science.adf0834

Nicola Micali, Shaojie Ma, Mingfeng Li, Suel-Kee Kim, Xoel Mato-Blanco, Suvimal Kumar Sindhu, Jon I. Arellano, Tianliuyun Gao, Mikihito Shibata, Kevin T. Gobeske, Alvaro Duque, Gabriel Santpere, Nenad Sestan, Pasko Rakic. (2023). Molecular programs of regional specification and neural stem cell fate progression in macaque telencephalon. Science. DOI: 10.1126/science.adf3786

Brian R. Lee, Rachel Dalley, Jeremy A. Miller, Thomas Chartrand, Jennie Close, Rusty Mann, Alice Mukora, Lindsay Ng, Lauren Alfiler, Katherine Baker, Darren Bertagnolli, Krissy Brouner, Tamara Casper, Eva Csajbok, Nicholas Donadio, Stan L.W. Driessens, Tom Egdorf, Rachel Enstrom, Anna A. Galakhova, Amanda Gary, Emily Gelfand, Jeff Goldy, Kristen Hadley, Tim S. Heistek, Dijon Hill, Wen-Hsien Hou, Nelson Johansen, Nik Jorstad, Lisa Kim, Agnes Katalin Kocsis, Lauren Kruse, Michael Kunst, Gabriela León, Brian Long, Matthew Mallory, Michelle Maxwell, Medea McGraw, Delissa McMillen, Erica J. Melief, Gabor Molnar, Marty T. Mortrud, Dakota Newman, Julie Nyhus, Ximena Opitz-Araya, Attila Ozsvár, Trangthanh Pham, Alice Pom, Lydia Potekhina, Ram Rajanbabu, Augustin Ruiz, Susan M. Sunkin, Ildikó Szöts, Naz Taskin, Bargavi Thyagarajan, Michael Tieu, Jessica Trinh, Sara Vargas, David Vumbaco, Femke Waleboer, Sarah Walling-Bell, Natalie Weed, Grace Williams, Julia Wilson, Shenqin Yao, Thomas Zhou, Pál Barzó, Trygve Bakken, Charles Cobbs, Nick Dee, Richard G. Ellenbogen, Luke Esposito, Manuel Ferreira, Nathan W. Gouwens, Benjamin Grannan, Ryder P. Gwinn, Jason S. Hauptman, Rebecca Hodge, Tim Jarsky, C. Dirk Keene, Andrew L. Ko, Anders Rosendal Korshoej, Boaz P. Levi, Kaare Meier, Jeffrey G. Ojemann, Anoop Patel, Jacob Ruzevick, Daniel L. Silbergeld, Kimberly Smith, Jens Christian Sørensen, Jack Waters, Hongkui Zeng, Jim Berg, Marco Capogna, Natalia A. Goriounova, Brian Kalmbach, Christiaan P.J. de Kock, Huib D. Mansvelder, Staci A. Sorensen, Gabor Tamas, Ed S. Lein, Jonathan T. Ting. (2023). Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex. Science. DOI: 10.1126/science.adf6484

Thomas Chartrand, Rachel Dalley, Jennie Close, Natalia A. Goriounova, Brian R. Lee, Rusty Mann, Jeremy A. Miller, Gabor Molnar, Alice Mukora, Lauren Alfiler, Katherine Baker, Trygve E. Bakken, Jim Berg, Darren Bertagnolli, Thomas Braun, Krissy Brouner, Tamara Casper, Eva Adrienn Csajbok, Nick Dee, Tom Egdorf, Rachel Enstrom, Anna A. Galakhova, Amanda Gary, Emily Gelfand, Jeff Goldy, Kristen Hadley, Tim S. Heistek, DiJon Hill, Nik Jorstad, Lisa Kim, Agnes Katalin Kocsis, Lauren Kruse, Michael Kunst, Gabriela Leon, Brian Long, Matthew Mallory, Medea McGraw, Delissa McMillen, Erica J. Melief, Norbert Mihut, Lindsay Ng, Julie Nyhus, Gáspár Oláh, Attila Ozsvár, Victoria Omstead, Zoltan Peterfi, Alice Pom, Lydia Potekhina, Ramkumar Rajanbabu, Marton Rozsa, Augustin Ruiz, Joanna Sandle, Susan M. Sunkin, Ildiko Szots, Michael Tieu, Martin Toth, Jessica Trinh, Sara Vargas, David Vumbaco, Grace Williams, Julia Wilson, Zizhen Yao, Pal Barzo, Charles Cobbs, Richard G. Ellenbogen, Luke Esposito, Manuel Ferreira, Nathan W. Gouwens, Benjamin Grannan, Ryder P. Gwinn, Jason S. Hauptman, Tim Jarsky, C. Dirk Keene, Andrew L. Ko, Christof Koch, Jeffrey G. Ojemann, Anoop Patel, Jacob Ruzevick, Daniel L. Silbergeld, Kimberly Smith, Staci A. Sorensen, Bosiljka Tasic, Jonathan T. Ting, Jack Waters, Christiaan P.J. de Kock, Huib D. Mansvelder, Gabor Tamas, Hongkui Zeng, Brian Kalmbach, Ed S. Lein. (2023). Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex. Science. DOI: 10.1126/science.adf0805

Xiaofeng Han, Shuxia Guo, Nan Ji, Tian Li, Jian Liu, Xiangqiao Ye, Yi Wang, Zhixi Yun, Feng Xiong, Jing Rong, Di Liu, Hui Ma, Yujin Wang, Yue Huang, Peng Zhang, Wenhao Wu, Liya Ding, Michael Hawrylycz, Ed Lein, Giorgio A. Ascoli, Wei Xie, Lijuan Liu, Liwei Zhang, Hanchuan Peng. (2023). Whole human-brain mapping of single cortical neurons for profiling morphological diversity and stereotypy. Science Advances. DOI: 10.1126/sciadv.adf3771

Juhyuk Park, Ji Wang, Webster Guan, Lars A. Gjesteby, Dylan Pollack, Lee Kamentsky, Nicholas B. Evans, Jeff Stirman, Xinyi Gu, Chuanxi Zhao, Slayton Marx, Minyoung E. Kim, Seo Woo Choi, Michael Snyder, David Chavez, Clover Su-Arcaro, Yuxuan Tian, Chang Sin Park, Qiangge Zhang, Dae Hee Yun, Mira Moukheiber, Guoping Feng, X. William Yang, C. Dirk Keene, Patrick R. Hof, Satrajit S. Ghosh, Matthew P. Frosch, Laura J. Brattain, Kwanghun Chung. (2022). Integrated platform for multi-scale molecular imaging and phenotyping of the human brain. bioRxiv. DOI: 10.1101/2022.03.13.484171

Márton Rózsa, Martin Tóth, Gáspár Oláh, Judith Baka, Rajmund Lákovics, Pál Barzó, Gábor Tamás. (2023). Temporal disparity of action potentials triggered in axon initial segments and distal axons in the neocortex. Science Advances. DOI: 10.1126/sciadv.ade4511

René Wilbers, Verjinia D. Metodieva, Sarah Duverdin, Djai B. Heyer, Anna A. Galakhova, Eline J. Mertens, Tamara D. Versluis, Johannes C. Baayen, Sander Idema, David P. Noske, Niels Verburg, Ronald B. Willemse, Philip C. de Witt Hamer, Maarten H. P. Kole, Christiaan P. J. de Kock, Huibert D. Mansvelder, Natalia A. Goriounova. (2023). Human voltage-gated Na ⁺ and K ⁺ channel properties underlie sustained fast AP signaling. Science Advances. DOI: 10.1126/sciadv.ade3300

René Wilbers, Anna A. Galakhova, Stan L.W. Driessens, Tim S. Heistek, Verjinia D. Metodieva, Jim Hagemann, Djai B. Heyer, Eline J. Mertens, Suixin Deng, Sander Idema, Philip C. de Witt Hamer, David P. Noske, Paul van Schie, Ivar Kommers, Guoming Luan, Tianfu Li, Yousheng Shu, Christiaan P.J. de Kock, Huibert D. Mansvelder, Natalia A. Goriounova. (2023). Structural and functional specializations of human fast-spiking neurons support fast cortical signaling. Science Advances. DOI: 10.1126/sciadv.adf0708

Eline J. Mertens, Yoni Leibner, Jean Pie, Anna A. Galakhova, Femke Waleboer, Julia Meijer, Tim S. Heistek, René Wilbers, Djai Heyer, Natalia A. Goriounova, Sander Idema, Matthijs B. Verhoog, Brian E. Kalmbach, Brian R. Lee, Ryder P. Gwinn, Ed S. Lein, Eleonora Aronica, Jonathan Ting, Huibert D. Mansvelder, Idan Segev, Christiaan P.J. de Kock. (2023). Morpho-electric and computational properties of three types of human hippocampal CA1 pyramidal neurons. bioRxiv. DOI: 10.1101/2023.10.05.561029