HCA Data Explorer

Single-cell Transcriptome Atlas of Testis Aging

Updated December 16, 2022

Unhealthy aging of testis seriously affects fertility and life quality of older men, while its interventions depend on in-depth knowledge of the molecular and functional changes of various testicular cell types. Here, we profile human testicular single-cell transcriptomes from young adult, healthy old men and late-onset hypogonadism (LOH) patients, and identified the somatic cells underwent a greater change than germ cells.

Liangyu ZhaoShanghai Jiao Tong University School of Medicinezhaoly37@mail.sysu.edu.cn

NA

Liangyu Zhao (Experimental Scientist)1
1Shanghai Jiao Tong University School of Medicine
Rachel Schwartz

To reference this project, please use the following link:

https://explore.data.humancellatlas.org/projects/e88714c2-2e78-49da-8146-5a60b50628b4
None
INSDC Project Accessions:GEO Series Accessions:INSDC Study Accessions:

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Analysis Portals

None

Project Label

atlasOfTestisAging

Species

Homo sapiens

Sample Type

specimens

Anatomical Entity

testis

Organ Part

Unspecified

Selected Cell Types

Unspecified

Disease Status (Specimen)

3 disease statuses

Disease Status (Donor)

3 disease statuses

Development Stage

human adult stage

Library Construction Method

10x 3' v3

Nucleic Acid Source

single cell

Paired End

false

Analysis Protocol

analysis_protocol_1

File Format

3 file formats

Cell Count Estimate

23.1k

Donor Count

5
fastq.gz10 file(s)tar1 file(s)xlsx1 file(s)