Transcriptomic and clonal characterization of T cells in the human central nervous system.
Tissues develop unique homeostatic immune states through specific recruitment of immune cells that are further shaped by the tissue environment. Single-cell RNA of healthy cerebrospinal fluid (CSF) and single-nucleus RNA sequencing of brain parenchyma was used to profile the T cell state in the human central nervous system (CNS).
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Atlas
Analysis Portals
NoneProject Label
TCellsHumanCentralNervousSystemSpecies
Homo sapiens
Sample Type
specimens
Anatomical Entity
brain
Organ Part
Selected Cell Types
Unspecified
Disease Status (Specimen)
normal
Disease Status (Donor)
Development Stage
human adult stage
Library Construction Method
10x 3' v3 sequencing
Nucleic Acid Source
single cell
Paired End
falseAnalysis Protocol
optimus_post_processing_v1.0.0, optimus_v4.2.3File Format
Cell Count Estimate
50.5kDonor Count
3