Fate-mapping within human iPSC-derived kidney organoids reveals conserved mammalian nephron progenitor lineage relationships.
Updated December 1, 2022Reprogramming, CRISPR/Cas9 gene-editing, organoid technologies and single-cell RNA sequencing technology were combined to study the nephron lineage in a human context.
Sara E Howden1
Jessica M Vanslambrouck1
Sean B Wilson1
Ker Sin Tan1
Melissa H Little1
1Murdoch Children's Research Institute
Ami Day
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Analysis Portals
NoneProject Label
GSE119561_KidneyOrganoidsNephronLineageSpecies
Homo sapiens
Sample Type
organoids
Anatomical Entity
skin of body
Organ Part
skin of prepuce of penis
Selected Cell Types
Unspecified
Model Organ
kidney
Disease Status (Specimen)
normal
Disease Status (Donor)
normal
Development Stage
human adult stage
Library Construction Method
10x 3' v2
Nucleic Acid Source
single cell
Paired End
falseAnalysis Protocol
analysis_protocolFile Format
4 file formats
Cell Count Estimate
5.4kDonor Count
1fastq.gz10 file(s)mtx.gz2 file(s)tsv.gz4 file(s)xlsx1 file(s)