HCA Data Explorer

Defining the Activated Fibroblast Population in Lung Fibrosis Using Single Cell Sequencing.

Updated July 19, 2023

Single-cell RNA sequencing was applied to identify distinct and dynamic cell populations, including an in-depth analysis of the fibroblast population, in lung fibrosis.

Lori MortonRegeneron Pharmaceuticals, Incorporatedlori.morton@regeneron.com
Rebecca Peyser1
Scott MacDonnell1
Yinglin Gao1
Luis Cheng1
Yong Kim1
Theodore Kaplan1
Qin Ruan1
Yi Wei1
Min Ni1
Christina Adler1
Wen Zhang1
Kishor Devalaraja-Narashimha1
Justin Grindley1
Gabor Halasz1
Lori Morton1
1Regeneron Pharmaceuticals, Incorporated
Ami Day

To reference this project, please use the following link:

https://explore.data.humancellatlas.org/projects/b4a7d12f-6c2f-40a3-9e35-9756997857e3
None
INSDC Project Accessions:GEO Series Accessions:INSDC Study Accessions:

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Analysis Portals

None

Project Label

Lung_Fibroblasts

Species

Mus musculus

Sample Type

specimens

Anatomical Entity

lung

Organ Part

Unspecified

Selected Cell Types

Unspecified

Disease Status (Specimen)

2 disease statuses

Disease Status (Donor)

2 disease statuses

Development Stage

adult

Library Construction Method

10x 3' v2

Nucleic Acid Source

single cell

Paired End

false

File Format

5 file formats

Cell Count Estimate

18.4k

Donor Count

11
bam11 file(s)fastq.gz33 file(s)loom12 file(s)tar1 file(s)xlsx1 file(s)