Dissecting the Global Dynamic Molecular Profiles of Human Fetal Kidney Development by Single-Cell RNA Sequencing

To investigate the gene expression profiles of human fetal kidney development, Wang et al. performed single-cell RNA-seq for >3,000 renal cells. They highlight the heterogeneity of cap mesenchyme and regulatory factors in nephron formation. The results reveal cell-type-specific risk genes in congenital renal diseases.

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