Single cell RNA-sequencing on healthy and IPF lung mesenchymal cells.
Updated September 23, 2021Single cell lung suspensions of explanted healthy and IPF donor lung tissue were generated. scRNA-seq was performed on EPCAM negative live cells sorted by FACS. Puried mesenchymal cells were clustered to evaluate the mesenchymal cell sub-clusters Overall design: To investigate pulmonary fibroblast lineage and the subtypes in human healthy and IPF lungs, mesenchymal cells (EPCAM/CD31/CD45-) were collected from five lungs from healthy donors and five lungs from IPF patients, single cell RNA-sequencing was performed on the purified mesenchymal cells.
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Analysis Portals
NoneProject Label
healthyIPFLungMesenchymalCellsSpecies
Sample Type
Anatomical Entity
Organ Part
Selected Cell Types
Disease Status (Specimen)
Disease Status (Donor)
Development Stage
Library Construction Method
Nucleic Acid Source
Paired End
falseAnalysis Protocol
analysis_protocol_1File Format
Cell Count Estimate
3.7kDonor Count
10